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Image Search Results
Journal: bioRxiv
Article Title: Gene Therapy Mediated Partial Reprogramming Extends Lifespan and Reverses Age-Related Changes in Aged Mice
doi: 10.1101/2023.01.04.522507
Figure Lengend Snippet: a . Measurement of DNA methylation age acceleration in liver ( left panel) and heart ( right panel) from control doxycycline treated mice (Control-Dox) or TRE- OSK mice using LUC epigenetic clocks trained on the indicated tissues. b . Human keratinocytes transduced with lentivirus at 2 different MOIs (0.5 and 1.0) expressing OSK showed epigenetic age reversal as compared to control GFP transduced or non-transduced (WT) cells. n=2 technical repeats for each group. One-Way ANOVA with Holm-Šídák’s multiple comparisons test. ns - not significant; *** p <0.001.
Article Snippet:
Techniques: DNA Methylation Assay, Control, Transduction, Expressing